Potential Protection by Antioxidants of the Action of Tobacco Smoke on the Metabolism of Cultured Bovine Lenses

Volume 3 • Issue 2 • 1000124 afflict smokers [2]. There has been suggestion that oxidative damage caused by accumulation of Fenton reagents (iron and copper) in the lens can cause lens damage and possibly cataract [3]. The lenses of experimental animals (Wistar rats) showed significantly decreased zinc and increased iron, and calcium concentration relative to those of sham exposed controls. However, no significant difference was found in the copper contents of the lenses. Distinct histopathological changes such as hyperplasia of epithelial cells and elevations of calcium concentration detected in the lenses of experimental group animals suggested that the lens damage was a result of in-vivo exposure to tobacco smoke. The